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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1724344	Entasis Therapeutics Holdings Inc.	ETTX	()	4

Insiders

Cik	Name	Reported Address	Director	Officer	Large Shareholder	Other
1249153	Dennis Henner	101 Main Street, 12Th Floor Cambridge MA 02142	No	No	Yes	No
1252523	Robert Liptak	101 Main Street, 12Th Floor Cambridge MA 02142	No	No	Yes	No
1252525	Kurt Wheeler	101 Main Street, 12Th Floor Cambridge MA 02142	No	No	Yes	No
1431403	Nicholas Simon	101 Main Street, 12Th Floor Cambridge MA 02142	No	No	Yes	No
1597143	Clarus Lifesciences Iii, L.p.	101 Main Street, Suite 1210 Cambridge MA 02142	No	No	Yes	No
1620148	Clarus Ventures Iii Gp, L.p.	101 Main Street, Suite 1210 Cambridge MA 02142	No	No	Yes	No
1664852	Scott Requadt	101 Main Street, 12Th Floor Cambridge MA 02142	No	No	Yes	No
1664942	Clarus Ventures Iii, Llc	101 Main Street, Suite 1210 Cambridge MA 02142	No	No	Yes	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
Common Stock	Acquisiton	2018-09-28	361,829	$0.00	361,829	No	4	C	Indirect	See Footnote
Common Stock	Acquisiton	2018-09-28	323,341	$0.00	685,170	No	4	C	Indirect	See Footnote
Common Stock	Acquisiton	2018-09-28	412,583	$0.00	1,170,010	No	4	C	Indirect	See Footnote
Common Stock	Acquisiton	2018-09-28	453,395	$15.00	1,623,405	No	4	P	Indirect	See Footnote

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	C	Indirect	See Footnote
No	4	C	Indirect	See Footnote
No	4	C	Indirect	See Footnote
No	4	P	Indirect	See Footnote

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Series B Convertible Preferred Stock	Disposition	2018-09-28	7,500,000	$0.00	361,829	$0.00
Common Stock	Series B-1 Tranche A Convertible Preferred Stock	Disposition	2018-09-28	6,702,213	$0.00	323,341	$0.00
Common Stock	Series B-1 Tranche B Convertible Preferred Stock	Disposition	2018-09-28	8,552,024	$0.00	412,583	$0.00

Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
No	4	C	Indirect
No	4	C	Indirect
No	4	C	Indirect

Footnotes

Each share of Series B Preferred Stock, Series B-1 Tranche A Convertible Preferred Stock and Series B-1 Tranche B Convertible Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a 20.728-for-one basis upon the closing of the Issuer's initial public offering. The Preferred Stock had no expiration date.
The reportable securities are held directly by Clarus Lifesciences III, L.P. ("Clarus III"). Clarus Ventures III GP, L.P. ("Clarus III GP") is the sole general partner of Clarus III. Clarus Ventures III, LLC ("Clarus III GP LLC") is the sole general partner of Clarus III GP. Nicholas Galakatos, Dennis Henner, Robert Liptak, Scott Requadt, Nicholas Simon, and Kurt Wheeler are the managing directors of Clarus III GP LLC (the "Managing Members"). Each of Clarus III GP, Clarus III GP LLC and the Managing Members may be deemed to beneficially own the securities held by Clarus III. Each of Clarus III GP, Clarus III GP LLC and the Managing Members disclaims beneficial ownership of these securities, except to the extent of their respective pecuniary interests therein.
This number includes an aggregate of 72,257 shares of Common Stock received upon the conversion of the Issuer's Preferred Stock as payment of the accrued dividends through September 27, 2018. No dividends will accrue after September 27, 2018.