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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1674365	Aptinyx Inc.	APTX	()	4

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1253886	G Patrick Enright	C/O Longitude Capital Partners Ii, Llc 2740 Sand Hill Rd 2Nd Floor Menlo Park CA 94025		Yes	No	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
Common Stock	Acquisiton	2018-06-25	1,047,450	$0.00	1,047,450	No	4	C	Indirect	By: Longitude Venture Partners II, L.P.
Common Stock	Acquisiton	2018-06-25	1,197,076	$0.00	2,244,526	No	4	C	Indirect	By: Longitude Venture Partners II, L.P.
Common Stock	Acquisiton	2018-06-25	795,553	$0.00	3,040,079	No	4	C	Indirect	By: Longitude Venture Partners II, L.P.
Common Stock	Acquisiton	2018-06-25	150,000	$16.00	3,190,079	No	4	P	Indirect	By: Longitude Venture Partners II, L.P.

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	C	Indirect	By: Longitude Venture Partners II, L.P.
No	4	C	Indirect	By: Longitude Venture Partners II, L.P.
No	4	C	Indirect	By: Longitude Venture Partners II, L.P.
No	4	P	Indirect	By: Longitude Venture Partners II, L.P.

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Series A-1 Convertible Preferred Stock	Disposition	2018-06-25	28,895,188	$0.00	1,047,450	$0.00
Common Stock	Series A-2 Convertible Preferred Stock	Disposition	2018-06-25	33,022,786	$0.00	1,197,076	$0.00
Common Stock	Series B Convertible Preferred Stock	Disposition	2018-06-25	21,946,301	$0.00	795,553	$0.00

Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
No	4	C	Indirect
No	4	C	Indirect
No	4	C	Indirect

Footnotes

Each share of Series A-1 Convertible Preferred Stock, Series A-2 Convertible Preferred Stock and Series B Convertible Preferred Stock automatically converted into shares of Common Stock on a 27.58621-for-one basis immediately prior to the closing of the Issuer's initial public offering without payment or consideration. The shares of Series A-1 Convertible Preferred Stock, Series A-2 Convertible Preferred Stock and Series B Convertible Preferred Stock had no expiration date.
These shares are held directly by Longitude Venture Partners II, L.P. ("Longitude Venture II"). Longitude Capital Partners II, LLC ("Longitude Capital II") is the general partner of Longitude Venture II and may be deemed to share voting and investment power over the shares of the Issuer held by Longitude Venture II. Patrick Enright ("Mr. Enright") is a managing member of Longitude Capital II and may be deemed to share voting and investment power over the shares of the Issuer held by Longitude Venture II. Mr. Enright disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.
On June 25, 2018, Longitude Venture II purchased 150,000 shares of Common Stock of the Issuer at a price of $16.00 per share in the Issuer's initial public offering.