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Filing Details

Accession Number:: 0000930413-11-000885
Form Type:: 4
Zero Holdings:: No
Publication Time:: 2011-02-10 17:19:09
Reporting Period:: 2011-02-08

Filing Date:: 2011-02-10
Accepted Time:: 2011-02-10 17:19:09
SEC Url:: Form 4 Filing

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1337013	Infusystem Holdings Inc	INFU	Surgical & Medical Instruments & Apparatus (3841)	203341405

Insiders

Cik	Name	Reported Address	Director	Officer	Large Shareholder	Other
1239607	R Jeffrey Jay	C/O Great Point Partners Llc 165 Mason Street, 3Rd Floor Greenwich CT 06830	No	No	Yes	No
1281446	Great Point Partners Llc	165 Mason Street, 3Rd Floor Greenwich CT 06830	No	No	Yes	No
1397513	David Kroin	C/O Great Point Partners Llc 165 Mason Street, 3Rd Floor Greenwich CT 06830	No	No	Yes	No

Reported Non-Derivative Transactions

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Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
Common Stock	Disposition	2011-02-08	110,252	$2.75	1,874,290	No	4	S	Indirect	By Biomedical Value Fund, L.P.
Common Stock	Disposition	2011-02-08	115,000	$2.75	1,955,000	No	4	S	Indirect	By Biomedical Offshore Value Fund, Ltd.
Common Stock	Disposition	2011-02-08	24,748	$2.75	420,710	No	4	S	Indirect	By Biomedical Institutional Value Fund, L.P.
Common Stock	Disposition	2011-02-10	1,874,290	$2.23	0	No	4	S	Indirect	By Biomedical Value Fund, L.P.
Common Stock	Disposition	2011-02-10	1,955,000	$2.23	0	No	4	S	Indirect	By Biomedical Offshore Value Fund, Ltd.
Common Stock	Disposition	2011-02-10	420,710	$2.23	0	No	4	S	Indirect	By Biomedical Institutional Value Fund, L.P.

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	S	Indirect	By Biomedical Value Fund, L.P.
No	4	S	Indirect	By Biomedical Offshore Value Fund, Ltd.
No	4	S	Indirect	By Biomedical Institutional Value Fund, L.P.
No	4	S	Indirect	By Biomedical Value Fund, L.P.
No	4	S	Indirect	By Biomedical Offshore Value Fund, Ltd.
No	4	S	Indirect	By Biomedical Institutional Value Fund, L.P.

Reported Derivative Holdings

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Sec. Name	Sec. Type	Price	Expiration Date	Amount	Remaning Holdings	Nature of Ownership
Warrant	Option (right to buy)	$0.00		900,000	900,000	Indirect
Warrant	Option (right to buy)	$0.00		766,666	766,666	Indirect
Common Stock	Option (right to buy)	$6.25	2011-04-11	900,000	900,000	Indirect
Common Stock	Option (right to buy)	$6.25	2011-04-11	766,666	766,666	Indirect

Expiration Date	Amount	Remaning Holdings	Nature of Ownership
	900,000	900,000	Indirect
	766,666	766,666	Indirect
2011-04-11	900,000	900,000	Indirect
2011-04-11	766,666	766,666	Indirect

Footnotes

Great Point Partners, LLC ("Great Point") is the investment manager of Biomedical Value Fund, L.P. ("BMVF") and by virtue of such status may be deemed to be the beneficial owner of the shares and options held by BMVF. Each of Dr. Jeffrey R. Jay, M.D. (Dr. "Jay"), as senior managing member of Great Point, and Mr. David Kroin ("Mr. Kroin"), as special managing member of Great Point, has voting and investment power with respect to the shares held by BMVF and may be deemed to be the beneficial owner of the shares and options held by BMVF. Great Point, Dr. Jay and Mr. Kroin disclaim beneficial ownership of the shares and options held by BMVF, except to the extent of any pecuniary interest, and this report shall not be deemed to be an admission that they are the beneficial owners of such securities.
Great Point is the investment manager of Biomedical Offshore Value Fund, Ltd. ("BOVF") and by virtue of such status may be deemed to be the beneficial owner of the shares and options held by BOVF. Each of Dr. Jay, as senior managing member of Great Point, and Mr. Kroin, as special managing member of Great Point, has voting and investment power with respect to the shares held by BOVF and may be deemed to be the beneficial owner of the shares and options held by BOVF. Great Point, Dr. Jay and Mr. Kroin disclaim beneficial ownership of the shares and options held by BOVF, except to the extent of any pecuniary interest, and this report shall not be deemed to be an admission that they are the beneficial owners of such securities.
Great Point is the investment manager of Biomedical Institutional Value Fund, L.P. ("BIVF") and by virtue of such status may be deemed to be the beneficial owner of the shares and options held by BIVF. Each of Dr. Jay, as senior managing member of Great Point, and Mr. Kroin, as special managing member of Great Point, has voting and investment power with respect to the shares held by BIVF and may be deemed to be the beneficial owner of the shares [and options] held by BIVF. Great Point, Dr. Jay and Mr. Kroin disclaim beneficial ownership of the shares and options held by BIVF, except to the extent of any pecuniary interest, and this report shall not be deemed to be an admission that they are the beneficial owners of such securities.
$.0000006.
On October 15, 2007, BMVF was assigned options to acquire warrants to purchase 899,999.64 shares of Common Stock of the Issuer by Great Point. Great Point acquired such options to acquire such warrants pursuant to an Option Agreement, dated as of October 12, 2007 (the "FTN Option Agreement"), by and between Great Point and FTN Midwest Securities Corp. Pursuant to the FTN Option Agreement, such options to acquire such warrants are exercisable upon the satisfaction of certain conditions, including the trading price for per of Common Stock of the Issuer equaling or exceeding $8.00 for any 20 out of 30 consecutive trading days.
Not applicable.
On October 15, 2007, BOVF was assigned options to acquire warrants to purchase 766,666.36 shares of Common Stock of the Issuer by Great Point. Great Point acquired such options to acquire warrants pursuant to the FTN Option Agreement. Pursuant to the FTN Option Agreement, such options to acquire such warrants are exercisable upon the satisfaction of certain conditions, including the trading price for per of Common Stock of the Issuer equaling or exceeding $8.00 for any 20 out of 30 consecutive trading days.
The exercise price of the warrants is subject to adjustment for dividends with respect to, or subdivisions, combinations, reclassifications of, the Issuer's common stock.
Exercisable immediately.