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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1370053	Anaptysbio Inc	ANAB	()	4

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1341382	N James Topper	C/O Frazier Healthcare Partners 601 Union Street, Suite 3200 Seattle WA 98101		Yes	No	Yes	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
Common Stock	Acquisiton	2017-01-31	2,228,377	$0.00	2,228,377	No	4	C	Indirect	see footnote
Common Stock	Acquisiton	2017-01-31	733,740	$0.00	733,740	No	4	C	Indirect	see footnote
Common Stock	Acquisiton	2017-01-31	209,095	$0.00	209,095	No	4	C	Indirect	see footnote
Common Stock	Acquisiton	2017-01-31	311,291	$15.00	1,045,031	No	4	P	Indirect	see footnote
Common Stock	Acquisiton	2017-01-31	88,709	$15.00	297,804	No	4	P	Indirect	see footnote

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	C	Indirect	see footnote
No	4	C	Indirect	see footnote
No	4	C	Indirect	see footnote
No	4	P	Indirect	see footnote
No	4	P	Indirect	see footnote

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Series B Preferred Stock	Disposition	2017-01-31	1,428,571	$0.00	1,428,571	$0.00
Common Stock	Series C Preferred Stock	Disposition	2017-01-31	604,055	$0.00	604,055	$0.00
Common Stock	Series C-1 Preferred Stock	Disposition	2017-01-31	195,751	$0.00	195,751	$0.00
Common Stock	Series D Preferred Stock	Disposition	2017-01-31	733,740	$0.00	733,740	$0.00
Common Stock	Series D Preferred Stock	Disposition	2017-01-31	209,095	$0.00	209,095	$0.00

Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
No	4	C	Indirect
No	4	C	Indirect
No	4	C	Indirect
No	4	C	Indirect
No	4	C	Indirect

Footnotes

In connection with the consummation of the Issuer's initial public offering on January 31, 2017, each share of Series B Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into one (1) share of Common Stock for no additional consideration, and had no expiration date. All shares of Common Stock issued upon conversion were aggregated.
Represents shares held by Frazier Healthcare V, L.P., an affiliate of Frazier Healthcare Ventures. Dr. Topper is a General Partner of Frazier Healthcare. Mr. Topper disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein.
Represents shares held by Frazier Healthcare VII, L.P., an affiliate of Frazier Healthcare Ventures. Dr. Topper is a General Partner of Frazier Healthcare. Mr. Topper disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein.
Represents shares held by Frazier Healthcare VII-A, L.P., an affiliate of Frazier Healthcare Ventures. Dr. Topper is a General Partner of Frazier Healthcare. Mr. Topper disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein.