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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
875320	Vertex Pharmaceuticals Inc / Ma	VRTX	Pharmaceutical Preparations (2834)	043039129

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1446372	M Paul Silva	C/O Vertex Pharmaceuticals Incorporated 130 Waverly St. Cambridge MA 02139	Svp & Corp Controller	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Acquisiton	2013-05-06	937	$39.05	12,687	No	4	M	Direct
Common Stock	Disposition	2013-05-06	230	$76.12	12,457	No	4	S	Direct
Commom Stock	Disposition	2013-05-06	707	$77.56	11,750	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	M	Direct
No	4	S	Direct
No	4	S	Direct

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Stock Option (right to buy)	Disposition	2013-05-06	937	$0.00	937	$39.05

Remaning Holdings	Exercise Date	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
2,813		2020-02-03	No	4	M	Direct

Reported Non-Derivative Holdings

Sec. Name	Remaning Holdings	Nature of Ownership	Explanation
Common Stock	169	Indirect	401(k)

Footnotes

Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.
Open market sales reported on this line occurred at a weighted average price of $76.12 (range $75.73 to $76.27).
Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.
Open market sales reported on this line occurred at a weighted average price of $77.56 (range $77.48 to $77.63).
The option vests in 16 quarterly installments beginning on 02/04/2010.