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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
885721	Express Scripts Inc	ESRX	Retail-Drug Stores And Proprietary Stores (5912)	431420563

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1235682	George Paz	C/O Express Scripts, Inc. One Express Way St. Louis MO 63121	Chairman, President & Ceo	Yes	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Acquisiton	2010-11-15	144,016	$8.66	757,920	No	4	M	Direct
Common Stock	Disposition	2010-11-15	144,016	$51.97	613,904	No	4	S	Direct
Common Stock	Acquisiton	2010-11-15	166,312	$9.40	780,216	No	4	M	Direct
Common Stock	Disposition	2010-11-15	166,312	$51.97	613,904	No	4	S	Direct
Common Stock	Acquisiton	2010-11-15	100,540	$9.66	714,444	No	4	M	Direct
Common Stock	Disposition	2010-11-15	100,540	$51.97	613,904	No	4	S	Direct
Common Stock	Acquisiton	2010-11-16	106,500	$9.66	720,404	No	4	M	Direct
Common Stock	Disposition	2010-11-16	106,500	$51.29	613,904	No	4	S	Direct
Common Stock	Acquisiton	2010-11-16	320,000	$10.70	933,904	No	4	M	Direct
Common Stock	Disposition	2010-11-16	320,000	$51.29	613,904	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	M	Direct
No	4	S	Direct
No	4	M	Direct
No	4	S	Direct
No	4	M	Direct
No	4	S	Direct
No	4	M	Direct
No	4	S	Direct
No	4	M	Direct
No	4	S	Direct

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Express Scripts, Inc. Common Stock	Non-Qualified Stock Option (Right-to-Buy)	Disposition	2010-11-15	144,016	$0.00	144,016	$8.66
Express Scripts, Inc. Common Stock	Non-Qualified Stock Option (Right-to-Buy)	Disposition	2010-11-15	166,312	$0.00	166,312	$9.40
Express Scripts, Inc. Common Stock	Non-Qualified Stock Option (Right-to-Buy)	Disposition	2010-11-15	100,540	$0.00	100,540	$9.66
Express Scripts, Inc. Common Stock	Non-Qualified Stock Option (Right-to-Buy)	Disposition	2010-11-16	106,500	$0.00	106,500	$9.66
Express Scripts, Inc. Common Stock	Non-Qualified Stock Option (Right-to-Buy)	Disposition	2010-11-16	320,000	$0.00	320,000	$10.70

Remaning Holdings	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
0	2011-02-10	No	4	M	Direct
0	2011-03-05	No	4	M	Direct
106,500	2012-03-01	No	4	M	Direct
0	2012-03-01	No	4	M	Direct
0	2012-04-11	No	4	M	Direct

Footnotes

The transactions reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by Reporting Person on May 14, 2010.
Reporting Person's shares beneficially owned have been adjusted to reflect the Company's 2-for-1 stock split effective on June 7, 2010.
The number of shares and exercise price have been adjusted to reflect the Company's 2-for-1 stock split effective on June 7, 2010.
Options vested in three (3) equal installments on December 31, 2004, December 31, 2005, and December 31, 2006.
Options vested in three (3) equal installments on the first three anniversaries of the grant date.
Options vested in three (3) equal installments on March 31, 2006, March 31, 2007, and March 31, 2008.
Employee stock option granted pursuant to Express Scripts, Inc. 2000 Long-Term Incentive Plan.