Filing Details

Accession Number:
0001193125-24-036334
Form Type:
13D Filing
Publication Date:
2024-02-13 19:00:00
Filed By:
Perceptive Advisors
Company:
Lyra Therapeutics Inc. (NASDAQ:LYRA)
Filing Date:
2024-02-14
SEC Url:
13D Filing
Ownership Summary

Please notice the below summary table is generated without human intervention and may contain errors. Please refer to the complete filing displayed below for exact figures.

Name Sole Voting Power Shared Voting Power Sole Dispositive Power Shared Dispositive Power Aggregate Amount Owned Power Percent of Class
Perceptive Advisors 0 12,757,563 0 12,757,563 12,757,563 24.3%
Joseph Edelman 0 12,757,563 0 12,757,563 12,757,563 24.3%
Perceptive Life Sciences Master Fund, Ltd 0 11,469,117 0 11,469,117 11,469,117 21.8%
Perceptive LS (A) 0 1,288,446 0 1,288,446 1,288,446 2.5%
Filing

 

 

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

 

 

SCHEDULE 13D/A

Under the Securities Exchange Act of 1934

(Amendment No. 3)*

 

 

Lyra Therapeutics, Inc.

(Name of Issuer)

Common Stock, $0.001 par value

(Title of Class of Securities)

55234L 105

(CUSIP Number)

Alexander Rakitin

Perceptive Advisors LLC

51 Astor Place, 10th Floor

New York, NY 10003

(646) 205-5340

(Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)

February 14, 2024

(Date of Event Which Requires Filing of this Statement)

 

 

If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. ☐

 

 

Note: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See Section 240.13d-7 for other parties to whom copies are to be sent.

 

 

 

*

The remainder of this cover page shall be filled out for a reporting persons initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed to be filed for the purpose of Section 18 of the Securities Exchange Act of 1934, as amended (Act) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

 

 

 


CUSIP No. 55234L 105

 

 1.    

 Names of Reporting Persons.

 

 Perceptive Advisors LLC

 2.  

 Check the Appropriate Box if a Member of a Group (See Instructions)

 (a) ☐  (b) ☒

 

 3.  

 SEC Use Only

 

 4.  

 Source of Funds (See Instructions)

 

 AF

 5.  

 Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e)

 

 ☐

 6.  

 Citizenship or Place of Organization

 

 Delaware

Number of

Shares  Beneficially 

Owned by

Each

Reporting

Person

With

 

    7.     

 Sole Voting Power

 

 0

    8.   

 Shared Voting Power

 

 12,757,563

    9.   

 Sole Dispositive Power

 

 0

   10.   

 Shared Dispositive Power

 

 12,757,563

11.    

 Aggregate Amount Beneficially Owned by Each Reporting Person

 

 12,757,563

12.  

 Check if the Aggregate Amount in Row (11) Excludes Certain Shares (See Instructions)

 

 ☐

13.  

 Percent of Class Represented by Amount in Row (11)

 

 24.3%

14.  

 Type of Reporting Person (See Instructions)

 

 IA


CUSIP No. 55234L 105

 

 1.    

 Names of Reporting Persons.

 

 Joseph Edelman

 2.  

 Check the Appropriate Box if a Member of a Group (See Instructions)

 (a) ☐  (b) ☒

 

 3.  

 SEC Use Only

 

 4.  

 Source of Funds (See Instructions)

 

 AF

 5.  

 Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e)

 

 ☐

 6.  

 Citizenship or Place of Organization

 

 United States of America

Number of

Shares  Beneficially 

Owned by

Each

Reporting

Person

With

 

    7.     

 Sole Voting Power

 

 0

    8.   

 Shared Voting Power

 

 12,757,563

    9.   

 Sole Dispositive Power

 

 0

   10.   

 Shared Dispositive Power

 

 12,757,563

11.    

 Aggregate Amount Beneficially Owned by Each Reporting Person

 

 12,757,563

12.  

 Check if the Aggregate Amount in Row (11) Excludes Certain Shares (See Instructions)

 

 ☐

13.  

 Percent of Class Represented by Amount in Row (11)

 

 24.3%

14.  

 Type of Reporting Person (See Instructions)

 

 IN


CUSIP No. 55234L 105

 

 1.    

 Names of Reporting Persons.

 

 Perceptive Life Sciences Master Fund, Ltd.

 2.  

 Check the Appropriate Box if a Member of a Group (See Instructions)

 (a) ☐  (b) ☒

 

 3.  

 SEC Use Only

 

 4.  

 Source of Funds (See Instructions)

 

 WC

 5.  

 Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e)

 

 ☐

 6.  

 Citizenship or Place of Organization

 

 Cayman Islands

Number of

Shares  Beneficially 

Owned by

Each

Reporting

Person

With

 

    7.     

 Sole Voting Power

 

 0

    8.   

 Shared Voting Power

 

 11,469,117

    9.   

 Sole Dispositive Power

 

 0

   10.   

 Shared Dispositive Power

 

 11,469,117

11.    

 Aggregate Amount Beneficially Owned by Each Reporting Person

 

 11,469,117

12.  

 Check if the Aggregate Amount in Row (11) Excludes Certain Shares (See Instructions)

 

 ☐

13.  

 Percent of Class Represented by Amount in Row (11)

 

 21.8%

14.  

 Type of Reporting Person (See Instructions)

 

 CO


CUSIP No. 55234L 105

 

 1.    

 Names of Reporting Persons.

 

 Perceptive LS (A), LLC

 2.  

 Check the Appropriate Box if a Member of a Group (See Instructions)

 (a) ☐  (b) ☒

 

 3.  

 SEC Use Only

 

 4.  

 Source of Funds (See Instructions)

 

 WC

 5.  

 Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e)

 

 ☐

 6.  

 Citizenship or Place of Organization

 

 Cayman Islands

Number of

Shares  Beneficially 

Owned by

Each

Reporting

Person

With

 

    7.     

 Sole Voting Power

 

 0

    8.   

 Shared Voting Power

 

 1,288,446

    9.   

 Sole Dispositive Power

 

 0

   10.   

 Shared Dispositive Power

 

 1,288,446

11.    

 Aggregate Amount Beneficially Owned by Each Reporting Person

 

 1,288,446

12.  

 Check if the Aggregate Amount in Row (11) Excludes Certain Shares (See Instructions)

 

 ☐

13.  

 Percent of Class Represented by Amount in Row (11)

 

 2.5%

14.  

 Type of Reporting Person (See Instructions)

 

 CO


Item 5. Interest in Securities of the Issuer

Item 5 of the Schedule 13D is amended and supplemented as follows:

 

  (a)

The information set forth in rows 11 and 13 of the cover pages to this Schedule 13D is incorporated by reference. The percentage set forth in row 13 is based on 52,563,127 outstanding shares of Common Stock as of November 1, 2023 as reported by the Issuer in its Form 10-Q filed with the Securities and Exchange Commission on November 7, 2023.

 

  (b)

The information set forth in rows 7 through 10 of the cover pages to this Schedule 13D is incorporated by reference.


SIGNATURES

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Dated: February 14, 2024

 

PERCEPTIVE ADVISORS LLC
By:  

/s/ Joseph Edelman

Name:   Joseph Edelman
Title:   Managing Member

/s/ Joseph Edelman

JOSEPH EDELMAN
PERCEPTIVE LIFE SCIENCES MASTER FUND, LTD.
By:   Perceptive Advisors LLC
By:  

/s/ Joseph Edelman

Name:   Joseph Edelman
Title:   Managing Member
PERCEPTIVE LS (A), LLC
By:   Perceptive LS GP, LLC
By:  

/s/ Joseph Edelman

Name:   Joseph Edelman
Title:   Member