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Filing Details

Accession Number:: 0001213900-14-006791
Form Type:: 4
Zero Holdings:: No
Publication Time:: 2014-09-19 19:52:36
Reporting Period:: 2014-09-17

Filing Date:: 2014-09-19
Accepted Time:: 2014-09-19 19:52:36
SEC Url:: Form 4 Filing

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1503802	Karyopharm Therapeutics Inc.	KPTI	Pharmaceutical Preparations (2834)	263931704

Insiders

Cik	Name	Reported Address	Director	Officer	Large Shareholder	Other
1591256	Andreas Hadjimichael	Simou Menardou 8, Ria Court 8, Office 101 6015 Larnaca G4	No	No	Yes	No
1591257	Amalia Hadjimichael	Simou Menardou 8, Ria Court 8, Office 101 6015 Larnaca G4	No	No	Yes	No
1591275	Marcin Czernik	Simou Menardou 8, Ria Court 8, Office 101 6015 Larnaca G4	No	No	Yes	No

Reported Non-Derivative Transactions

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Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
Common Stock	Disposition	2014-09-17	9,569	$40.26	2,925,793	No	4	S	Indirect	See Footnotes
Common Stock	Disposition	2014-09-18	2,778	$40.16	2,923,015	No	4	S	Indirect	See Footnotes

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	S	Indirect	See Footnotes
No	4	S	Indirect	See Footnotes

Footnotes

The prices reported in Column 4 are weighted average prices. The shares sold on September 17, 2014 were sold at prices ranging from $40.00 to $40.80, inclusive. The shares sold on September 18, 2014 were sold at prices ranging from $40.00 to $40.77, inclusive. The reporting persons undertake to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within each of the ranges set forth above.
Shares of Common Stock are owned directly by Plio Limited ("Plio"), which holds less than 10% of the outstanding Common Stock of the issuer. Plio's directors, Marcin Czernik, Andreas Hadjimichael and Amalia Hadjimichael, may be deemed to share voting and investment power and beneficial ownership of the shares of Common Stock directly owned by Plio. Gregory Jankilevitsch , the sole shareholder of Plio, may also be deemed to share voting and investment power and beneficial ownership of the shares of Common Stock directly owned by Plio. The shares owned by Plio do not include the 10,223,767 shares of the issuer's Common Stock held by Chione Limited, which has the same directors as Plio.
Each reporting person states that neither the filing of this Form 4 nor anything herein shall be deemed an admission that such person or any other person is, for purposes of Section 16 of the Securities Exchange Act of 1934, as amended (the "Act"), or otherwise, the beneficial owner of any securities covered by this Form 4. Beneficial ownership of the securities covered by this statement is disclaimed, except, with respect to any person, to the extent of the pecuniary interest of such person in such securities.
Each reporting person may be deemed to be a member of a group with respect to the issuer or securities of the issuer for purposes of Section 13(d) or 13(g) of the Act. Each reporting person declares that neither the filing of this Form 4 nor anything herein shall be construed as an admission that such person or any other person is, for the purposes of Section 13(d) or 13(g) of the Act or any other purpose, a member of a group with respect to the issuer or securities of the issuer.