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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
939767	Exelixis Inc	EXEL	Services-Commercial Physical & Biological Research (8731)	043257395

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1317711	M Lupe Rivera	C/O Exelixis, Inc. 170 Harbor Way, Po Box 511 South San Francisco CA 94083-0511	Evp, Operations	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Acquisiton	2010-12-17	25,000	$5.63	25,000	No	4	M	Direct
Common Stock	Disposition	2010-12-17	25,000	$8.50	0	No	4	S	Direct
Common Stock	Acquisiton	2010-12-17	4,427	$4.42	4,427	No	4	M	Direct
Common Stock	Disposition	2010-12-17	4,427	$8.50	0	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	M	Direct
No	4	S	Direct
No	4	M	Direct
No	4	S	Direct

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Option (right to buy)	Disposition	2010-12-17	25,000	$0.00	25,000	$5.63
Common Stock	Option (right to buy)	Disposition	2010-12-17	4,427	$0.00	4,427	$4.42

Remaning Holdings	Exercise Date	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
34,250	2010-08-05	2015-10-17	No	4	M	Direct
20,573	2010-02-26	2019-02-25	No	4	M	Direct

Reported Non-Derivative Holdings

Sec. Name	Remaning Holdings	Nature of Ownership	Explanation
Common Stock	2,963	Indirect	By 401(k) Plan

Footnotes

The sale reported on this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 11, 2009, as amended.
Represents 2,963 shares of Exelixis, Inc. common stock under the Exelixis, Inc. 401(k) Plan, pursuant to a plan statement date December 16, 2010.
The option, representing the right to purchase a total of 105,000 shares, became exercisable as to one hundred percent (100%) of the shares subject to the option on August 5, 2010.
The option, representing the right to purchase a total of 25,000 shares, became exercisable as to twenty five (25%) of the shares subject to the option on February 26, 2010 and the remaining shares have vested and continue to vest in 36 equal monthly installments thereafter.