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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
944809	Opko Health, Inc.	OPK	Pharmaceutical Preparations (2834)	752402409

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
898860	Al Et Md Phillip Frost	Opko Health, Inc. 4400 Biscayne Blvd. Miami FL 33137	Ceo & Chairman	Yes	Yes	Yes	No
1380896	Trust Investments Gamma Frost	4400 Biscayne Blvd. Miami FL 33137		No	No	Yes	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings
Common Stock	Acquisiton	2013-03-07	1,600	$7.29	121,257,854
Common Stock	Acquisiton	2013-03-07	1,500	$7.29	121,259,354
Common Stock	Acquisiton	2013-03-07	700	$7.30	121,260,054
Common Stock	Acquisiton	2013-03-07	3,100	$7.31	121,263,154
Common Stock	Acquisiton	2013-03-07	1,200	$7.32	121,264,354
Common Stock	Acquisiton	2013-03-07	2,900	$7.34	121,267,254
Common Stock	Acquisiton	2013-03-07	8,300	$7.34	121,275,554
Common Stock	Acquisiton	2013-03-07	2,900	$7.35	121,278,454
Common Stock	Acquisiton	2013-03-07	19,063	$7.36	121,297,517
Common Stock	Acquisiton	2013-03-07	237	$7.37	121,297,754
Common Stock	Acquisiton	2013-03-07	4,400	$7.39	121,302,154
Common Stock	Acquisiton	2013-03-07	600	$7.40	121,302,754
Common Stock	Acquisiton	2013-03-07	600	$7.42	121,303,354
Common Stock	Acquisiton	2013-03-07	4,400	$7.43	121,307,754

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	P	Indirect	See Footnote
No	4	P	Indirect	See Footnote
No	4	P	Indirect	See Footnote
No	4	P	Indirect	See Footnote
No	4	P	Indirect	See Footnote
No	4	P	Indirect	See Footnote
No	4	P	Indirect	See Footnote
No	4	P	Indirect	See Footnote
No	4	P	Indirect	See Footnote
No	4	P	Indirect	See Footnote
No	4	P	Indirect	See Footnote
No	4	P	Indirect	See Footnote
No	4	P	Indirect	See Footnote
No	4	P	Indirect	See Footnote

Reported Non-Derivative Holdings

Sec. Name	Remaning Holdings	Nature of Ownership	Explanation
Common Stock	15,490,546	Indirect	See Footnote

Footnotes

The securities are held by Frost Gamma Investments Trust, of which Phillip Frost M.D., is the trustee. Frost Gamma L.P. is the sole and exclusive beneficiary of Frost Gamma Investments Trust. Dr. Frost is one of two limited partners of Frost Gamma L.P. The general partner of Frost Gamma L.P. is Frost Gamma, Inc., and the sole shareholder of Frost Gamma, Inc. is Frost-Nevada Corporation. Dr. Frost is also the sole shareholder of Frost-Nevada Corporation. The reporting person disclaims beneficial ownership of these securities, except to the extent of any pecuniary interest therein and this report shall not be deemed an admission that the reporting person is the beneficial owner of these securities for purposes of Section 16 or for any other purpose.
These securities are owned directly by The Frost Group, LLC. Frost Gamma Investments Trust is a principal member of The Frost Group, LLC. The reporting person disclaims beneficial ownership of these securities, except to the extent of any pecuniary interest therein and this report shall not be deemed an admission that the reporting person is the beneficial owner of these securities for purposes of Section 16 or for any other purpose.